Pair Name	Sulforaphane, TNF-related apoptosis inducing ligand
Disease Info	[ICD-11: 2C82]	Prostate cancer		Investigative
Biological Phenomena	Inhibition-->Angiogenesis
Gene Regulation	Up-regulation	Expression	BAK1	hsa578
	Up-regulation	Expression	BAX	hsa581
	Down-regulation	Expression	BCL2	hsa596
	Down-regulation	Expression	BCL-xL	hsa598
	Up-regulation	Cleavage	CASP3	hsa836
	Down-regulation	Expression	CCNB1	hsa891
	Down-regulation	Expression	CDH13	hsa1012
	Down-regulation	Expression	CDK1	hsa983
In Vitro Model	PC-3	Prostate carcinoma	Homo sapiens (Human)	CVCL_0035
	LNCaP	Prostate carcinoma	Homo sapiens (Human)	CVCL_0395
In Vivo Model	Mice were inoculated with PC-3 cells (1×10⁶ per 100 AL medium) into the dorsolateral lobe of the prostatic capsule.
Result	The ability of sulforaphane to inhibit tumor growth, metastasis, and angiogenesis and to enhance the therapeutic potential of TRAIL suggests that sulforaphane alone or in combination with TRAIL can be used for the management of prostate cancer.